| Prefix with genetics | 20 |
| pounds | 6 |
| ... iguanas, restaurant chain | 29 |
| card up one's sleeve | 20 |
| make suitable for publication | 29 |
| opposite of pro | 15 |
| the "r" of rpg | 14 |
| mischief; early risers | 22 |
| one of the kray twins | 21 |
| fold in a sheet | 15 |
| the ..., series starring martin compston | 40 |
| sophia ..., arabesque actress | 29 |
| material used in rainwear | 25 |
| ... so simple, porridge brand | 29 |
| investigator | 12 |
| otorhinolaryngology | 19 |
| ... up your life, ... girls tune | 32 |
| part of a cap | 13 |
| corpulent | 9 |
| ted ..., sporting comedy with nick mohammed | 43 |
| precursor to angulate, cycle and pod | 36 |
| tab for a key ring | 18 |
| town on the firth of forth | 26 |
| rouses | 6 |
| aneurin bevan's baby | 20 |
| king of judea | 13 |
| colonial member | 15 |
| more, musically | 15 |
| chart | 5 |
| jelly-like substance | 20 |
| contends against | 16 |
| olympic venue in 2000 | 21 |
| mata ..., femme fatale | 22 |
| part of a fowl's throat | 23 |
| river of central europe | 23 |
| ... wallis, bouncing bomb boffin | 32 |
| yemen port native | 17 |
| petty objection | 15 |
| falls in flakes | 15 |
| craft trading platform | 22 |
| southend's county | 17 |
| printer consumables | 19 |
| up to no good | 13 |
| vince ..., former lib dem leader | 32 |
| puts in peril | 13 |
| assign | 6 |
| ... sauce, creation of levi roots | 33 |
| kingdom | 7 |
| duran duran album | 17 |
| poetically before | 17 |
| ..., i feel like a pair of curtains | 35 |
| andy mcnab's old unit | 21 |
| kiss from a rose singer | 23 |
| operating | 9 |
| jog | 3 |
| gravy brand | 11 |
| like a strong-smelling stilton? | 31 |
| they're proverbially hard | 25 |
| nickelodeon explorer | 20 |
| résumés | 9 |
| ... catchee monkey | 18 |
| pouch | 5 |
| sounds of incomprehension | 25 |
| comparatively cunning | 21 |
| ... chicken dinner | 18 |
| broken | 6 |
| learnt by earwigging | 20 |
| björn ..., abba tribute band | 29 |
| cart some distance back | 23 |
| love for a spaniard | 19 |
| ... bay buccaneers, nfl team | 28 |
| tuts from swinney? | 18 |
| encrustation | 12 |
| Unreliable narrators | 20 |
| Plugs | 5 |
| Too much, musically | 19 |
| With 99-Across, four timepieces [1931] | 38 |
| Wash out | 8 |
| Minute | 6 |
| Name on a box of fruit-flavored candy | 37 |
| Crazy Horse and kin | 19 |
| Frog-hopping-into-water sound | 29 |
| Feature of a Raggedy Ann doll | 29 |
| Wacky | 5 |
| Sauce in Philippine cuisine | 27 |
| Component of the immune system | 30 |
| Just manage, with "out" | 23 |
| One gemstone [1665] | 19 |
| Good name for a nuclear engineer? | 33 |
| "Ted Lasso" footballer Jamie ... | 32 |
| About to bloom | 14 |
| Performing, perhaps | 19 |
| TV host Joy | 11 |
| Modern-day Phoenicia | 20 |
| Many moons | 10 |
| Runner Down Under | 17 |
| 12 orbs [1889] | 14 |
| Hashtag's neighbor on a keyboard | 32 |
| Souvlaki go-with | 16 |
| "Real Time With Bill ..." | 25 |
| Six Basque villagers [1937] | 27 |
| Writer buried in a Baltimore churchyard | 39 |
| Part of the atmosphere above most weather | 41 |
| Slip in a warehouse | 19 |
| Stuff left behind by an old flame? | 34 |
| Patton crossed it in 1944 | 25 |
| Succor | 6 |
| Renovation need, perhaps | 24 |
| Two Iowans [1930] | 17 |
| Path to Machu Picchu | 20 |
| Atypical band instrument | 24 |
| Seasonal decoration from the Old French for "sparkle" | 53 |
| Mechanical catch | 16 |
| "La Vie en Rose" singer | 23 |
| Plant in a bloom | 16 |
| "Later, alligator!" | 19 |
| King with a golden touch | 24 |
| Have life | 9 |
| Upper body, to a sculptor | 25 |
| Urge forcefully | 15 |
| "... luck!" ["Go get 'em!"] | 27 |
| One of 51 written by Alexander Hamilton for the Federalist Papers | 65 |
| June celebration | 16 |
| Gutsy boldness | 14 |
| "10 ... or less" [supermarket line] | 35 |
| Arithmetic mean, for short | 26 |
| "... over!" ["Donkey Kong" message] | 35 |
| Joule fraction | 14 |
| Disco-lover on "The Simpsons" | 29 |
| Hint, in a way | 14 |
| "Give ... break!": 2 wds. | 25 |
| Eighth month, for short | 23 |
| "Teen Mom" channel: Abbr. | 25 |
| Actor Butterfield of "Nanny McPhee and the Big Bang" | 52 |
| Actress Thurman of "Pulp Fiction" | 33 |
| Animated sci-fi sitcom following Philip J. Fry that moved from Fox to Comedy Central, and now streams on Hulu | 109 |
| Phenomenon that may cause a flight delay | 40 |
| Farm field measure | 18 |
| Desert feature | 14 |
| Chemical suffix with "ox" or "brom" | 35 |
| Couple, in paparazzi lingo | 26 |
| Pull along the ground, say | 26 |
| Dell competitor from Taiwan | 27 |
| Like some old memories or clothes, say | 38 |
| "Hallmark Hall of ...," anthology TV series that moved from NBC to three other networks and now runs on Hallmark Channel | 120 |
| Actress Winslet of "Eternal Sunshine of the Spotless Mind" | 58 |
| Pre-birth chamber? | 18 |
| "Like ... of sunshine": 2 wds. | 30 |
| Classic Pontiac vehicle: Abbr. | 30 |
| The "G" of OMG | 14 |
| Napkin thickness | 16 |
| Caustic cleaning agent | 22 |
| Longitude's partner, for short | 30 |
| Playwright Levin | 16 |
| "One Tree ...," drama TV series that moved from The WB to The CW in 2006 | 72 |
| Uninvited picnic guest? | 23 |
| Cash dispenser in a bank lobby: Abbr. | 37 |
| ... mater [old school] | 22 |
| One of a pair at the dining table | 33 |
| It helps you reroute: Abbr. | 27 |
| Female neigh-er | 15 |
| Sheet where "X" marks the spot | 30 |
| Kilogram or pound, for short | 28 |
| She-sheep | 9 |
| Matcha or Darjeeling, e.g. | 26 |
| Swiss ... knife [multi-functional tool] | 39 |
| Light bulb unit that sounds like a question | 43 |
| "Hole in the ...," show that moved from Fox to Cartoon Network in 2010 | 70 |
| "Dancing with the ...," reality dance competition series that moved from ABC to Disney+ in 2022 | 95 |
| Back-to-school month, for short | 31 |
| Agree silently | 14 |
| Nabisco treat | 13 |
| Savings account addition, for short | 35 |
| "... Dad!," animated sitcom that moved from Fox to TBS in 2014 | 62 |
| Bird that symbolizes peace | 26 |
| E-mail address punctuation | 26 |
| Muhammad ..., "The Rumble in the Jungle" boxer | 46 |
| Volcanic outpour | 16 |
| Startup VIPs: Abbr. | 19 |
| Christmas tree's month, for short | 33 |
| Can material | 12 |
| "... Runner," 1982 sci-fi film | 30 |
| Hashtag letters of nostalgia | 28 |
| ... Bell [place to get a Crunchwrap Supreme] | 44 |
| Tesla product | 13 |
| "... had enough!" | 17 |
| Receptionist from "The Office," lovingly | 40 |
| ... fail [grand disaster] | 25 |
| "She," in Portugal | 18 |
| Young fellow, in Aberdeen | 25 |
| Homer Simpson's neighbor | 24 |
| ... jar [food-preserving jar] | 29 |
| ... Bunny [Bugs Bunny's girlfriend] | 35 |
| Milky gemstone | 14 |
| Relating to the nose | 20 |
| Actor KJ ... from "Riverdale" | 29 |
| Frying utensil | 14 |
| Cheerleader's prop, when repeated twice | 39 |
| Cupid's instrument? | 19 |
| "..., gator!" [bye] | 19 |