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"vex" - Word "5" letter starting with "A" and ending with "D"

Definition
be a mystery or bewildering to;
subject to prolonged examination, discussion, or deliberation; "vex the subject of the death penalty"
change the arrangement or position of
disturb the peace of mind of; afflict with mental agitation or distress; "I cannot sleep--my daughter's health is worrying me"
cause annoyance in; disturb, especially by minor irritations;

8 Definition

Irk
Bug
annoy
Get to
irritate
Exasperate
anger or annoy
irritate former spouse with victory first

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