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"rheumatism" - Word "5" letter starting with "A" and ending with "D"
| Definition |
| any painful disorder of the joints or muscles or connective tissues |
| a chronic autoimmune disease with inflammation of the joints and marked deformities; something (possibly a virus) triggers an attack on the synovium by the immune system, which releases cytokines that stimulate an inflammatory reaction that can lead to the destruction of all components of the joint |